What is the most common transfusion threshold for stable, non-bleeding adults?

• A. 5 g/dL
• B. 7 g/dL
• C. 9 g/dL
• D. 10 g/dL

Answer: (B)

The typical transfusion trigger for stable, non-bleeding adults is a hemoglobin level around 7 g/dL. This aligns with evidence from trials showing a restrictive transfusion approach reduces unnecessary transfusions without worsening outcomes in most patients. The idea is to balance improving oxygen delivery with the risks of transfusion, such as reactions and infections. In practice, 7 g/dL is used for most stable patients, while higher thresholds (for example, around 8 g/dL or more) may be chosen for those with symptomatic anemia or significant cardiovascular disease or ongoing hypoxia. The other numbers represent more liberal thresholds that aren’t routinely used in stable patients.